Publication of the regulatory toxicology call for offers
- February 18, 2025
A regulatory preclinical toxicology study aimed at assessing the overall effects of HEPHA-440 on the organs will be entrusted to a specialized company certified in Good Laboratory Practices (GLP). This study, conducted in two phases in rabbits—whose sensitivity to LPS is similar to that of humans—will include: 1. A dose-escalation study, 2. A detailed analysis of acute and long-term toxicity in both males and females, in accordance with GLP standards. The results of these experiments will be crucial to ensuring safe administration in humans and obtaining approval from health authorities. The call for offers has been published on the French government procurement platform (PLACE) and will remain open for one month.
Annual Scientific Meeting
- February 17, 2025
At the media library of the Rockefeller Faculty in Lyon, the first annual scientific day of the SyStInn RHU project was held. This event brought together all the teams involved, representatives of partner institutions, and ANR members in charge of monitoring. The progress made in each work package was presented, along with the upcoming steps. This moment was also an opportunity to discuss the challenges encountered and the future directions of the project.
Signature of the consortium agreement
- December 3, 2024
A consortium agreement has been approved and signed by the four partner institutions of the project and submitted to the funding organization, the ANR. This document defines the rules of collaboration and specifies the rights and obligations of each party, particularly regarding intellectual property.
Kick-off Meeting
- April 24, 2024
The scientific teams, representatives from partner institutions, and ANR members responsible for monitoring the SyStInn RHU gathered to review the project’s objectives and agree on the provisional timeline for the next five years.
